Key member of the Translational Research team applying computational approaches to derive biological and translational insights from complex preclinical and clinical datasets, focusing on biomarkers and drug response mechanisms.
Compensation
$149,000—$186,000 USD
Responsibilities
Apply computational approaches to uncover biomarkers, mechanisms of drug response and resistance, pharmacodynamic effects, and therapeutic strategies.
Analyze and integrate bulk and single-cell sequencing, spatial transcriptomics, and other molecular data with biomarker, pathology, and efficacy/response outcomes.
Develop reproducible analytical workflows and partner on AI-enabled solutions.
Partner across Translational Research, Translational Medicine, Discovery, Bioinformatics, and Information Sciences.
Perform cross-study analyses to identify reproducible biological signals.
Seeking a Senior Scientist or Principal Lab Group Head to drive biomarker and drug development and/or translational research efforts in multiple sclerosis using molecular and cellular phenotyping.
Compensation
The expected salary range for this position based on the primary location of California is $120,700 - 224,100 (Senior Scientist) and $141,500 - 262,900 (Principal Scientist).
Responsibilities
Identify new targets and biomarkers in support of drug development projects in multiple sclerosis.
Lead efforts to support clinical trials, lead data generation and analyses within internal studies.
Lead external academic collaborations relating to understanding disease pathogenesis in multiple sclerosis.
Work in close partnership across various functions including Research, Bioanalytical Assay Department, Diagnostics, Clinical, Biostatistics, Computational Science, Regulatory and with external partners.
Provide effective communication with presentations at cross-functional teams, internal review committees, and external conferences.
Lead biomarker and drug development research in multiple sclerosis within the Translational Medicine department.
Compensation
The expected salary range for this position based on the primary location of California is $120,700 - 224,100 (Senior Scientist) and $141,500 - 262,900 (Principal Scientist). Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance.
Responsibilities
Identify new targets and biomarkers to support drug development projects in multiple sclerosis
Lead efforts to support clinical trials, data generation and analyses within internal studies
Lead external academic collaborations relating to understanding disease pathogenesis in multiple sclerosis
Integrate biomarkers into clinical trials and/or with target identification or validation
Provide effective communication through presentations, reports, regulatory filings and scientific publications
Requirements
PhD in Neuroscience and/or Immunology or related field
Nice to have: prior experience in multiple sclerosis
Support the development and expansion of spatial biology capabilities for preclinical and translational biomarker discovery in the Oncology Research department.
Compensation
Pay: $38.93/Hour
Responsibilities
Develop, optimize, and execute high-plex tissue-based assays, including multiplex immunofluorescence and other spatial protein profiling approaches in human and mouse tissues.
Design and optimize multiplex antibody panels, including antibody selection, staining conditions, controls, panel compatibility, tissue-specific optimization, and assay performance.
Support the establishment and application of spatial transcriptomics and emerging spatial profiling technologies, including assay and data QC.
Develop integrated workflows spanning tissue preparation, staining, imaging, spatial profiling, and quantitative analysis, troubleshooting assays to improve robustness, reproducibility, and data quality.
Support acquisition and analysis of whole-slide, multiplex, and spatial imaging datasets, including tissue annotation, cell segmentation, phenotyping, spatial quantification, and visualization.
Requirements
Bachelor’s or Master’s degree in Biology, Histotechnology, Pathology, Biomedical Sciences, or a related discipline
Support the development and expansion of spatial biology capabilities for preclinical and translational biomarker discovery.
Compensation
Pay Rate Range: $38.66 - $41.42/hr. on W2.
Responsibilities
Develop, optimize, and execute high-plex tissue-based assays, including multiplex immunofluorescence and other spatial protein profiling approaches in human and mouse tissues.
Design and optimize multiplex antibody panels, including antibody selection, staining conditions, controls, panel compatibility, tissue-specific optimization, and assay performance.
Support the establishment and application of spatial transcriptomics and emerging spatial profiling technologies, including assay and data QC.
Develop integrated workflows spanning tissue preparation, staining, imaging, spatial profiling, and quantitative analysis, troubleshooting assays to improve robustness, reproducibility, and data quality.
Support acquisition and analysis of whole-slide, multiplex, and spatial imaging datasets, including tissue annotation, cell segmentation, phenotyping, spatial quantification, and visualization.
Requirements
Bachelor's or Master's degree in Biology, Histotechnology, Pathology, Biomedical Sciences, or a related discipline.
Nice to have: High-plex/multiplex protein imaging
Nice to have: Spatial transcriptomics or related spatial gene-expression technologies
The Vice President, Gene Editing Core leads a highly cross-functional team applying state-of-the-art genomic and molecular biology tools to advance genome editing therapies. This role oversees the planning, execution, and delivery of projects to support early research and development studies.
Compensation
The base salary for this position is expected to range between $327,100.00 - $399,900.00 USD per year.
Responsibilities
Creates and leads vision of genomics innovation to support research in developing gene-editing therapies
Collaborates across Platform Innovation and Delivery Innovation to advance novel nucleases, insertion strategies, new technologies, and delivery advancements
Supports Screening efforts generating data in support of advancing the pipeline programs and platform improvements including guide RNA, messenger RNA, and delivery optimization
Oversees NGS production efforts, running AMP-seq, off-target discovery, off-target confirmation, and structural variant analysis
Partners with computational biology, software engineering, and automation on data analysis, data capture, and workflow optimization
Investigate cellular and molecular mechanisms regulating immune cell responses and interactions within tissue microenvironments, design and perform in vivo experiments, and develop innovative research projects to advance immune cell reprogramming.
Compensation
The New York City, NY base pay range for a new hire in this role is Postdoctoral Fellow = $93,000.00 & Scientist I = $120,000 - $150,000. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.
Responsibilities
Investigate the cellular and molecular mechanisms regulating immune cell responses and interactions within tissue microenvironments.
Design and perform in vivo experiments using mouse models.
Characterize immune cell differentiation, function, and interactions with other cells.
Apply advanced experimental approaches, including molecular biology, single-cell sequencing, spatial transcriptomics, and genetic perturbation technologies.
Develop and test hypotheses to understand how immune cells and local tissue environments reciprocally shape each other’s behavior and function.
Requirements
PhD in molecular biology, bioengineering, genetics, cell biology, immunology, or a related field.
Nice to have: pooled CRISPR screens
Nice to have: in vivo perturbation strategies
Nice to have: functional genomics
Nice to have: immune cell differentiation
Skills
PhD Position
Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol (IGTP) · Posted Nov 3, 2026
Lead a predoctoral research project on decellularized and re-endothelialized human vascular grafts.
Compensation
The gross annual remuneration associated with this position will be established according to the applicable conditions and distributed in 12 monthly payments: €23,700 gross/year in the first year, €24,500 gross/year in the second year and €26,000 gross/year in the third year.
Responsibilities
Perform laboratory techniques and protocols related to cell culture, tissue engineering, decellularization and re-endothelialization, flow cytometry, histology, immunohistochemistry and molecular biology.
Participate in the development and optimization of re-endothelialization protocols and vascular graft conditioning using bioreactor systems.
Support experimental procedures in large animal models (porcine and ovine), including vascular graft implantation, angiographic/echocardiographic follow-up, and sample collection and processing.
Conduct statistical analysis, processing and interpretation of experimental data, including participation in omics data analysis.
Write and review scientific manuscripts, conference communications and research projects, and participate in other scientific dissemination activities.
Requirements
Bachelor's in Veterinary Medicine or Medicine
Bachelor's in Biology, Biochemistry, Biotechnology, Biomedicine or related biomedical sciences
Senior /Principal Scientist- (Multiple Sclerosis)Genentech · South San Francisco, US
Postdoctoral Fellow/ Scientist I, T Cell Biology and Tissue ImmunologyBiohub · New York, US
PhD PositionInstitut d'Investigació en Ciències de la Salut Germans Trias i Pujol (IGTP) · Badalona, Spain