Biophysical characterization jobs

Principal Scientist (m/f/d) Protein Engineering

BoehringerPRD · Posted Nov 12, 2026

Open

Vienna, Vienna, Austria
Full-time · Senior
€91K–€91K per year
3–5 years

Principal Scientist (m/f/d) Protein Engineering

BoehringerPRD · Posted Nov 12, 2026

Open

Vienna, Vienna, Austria
Full-time · Senior
€91K–€91K per year
3–5 years

PDRA

Durham University · Posted Nov 10, 2026

Open

Durham, Durham, United Kingdom
On-site
Full-time · Mid
Full-time for 15 months.

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Post-Doctoral Research Assistant at the Centre for Programmable Biological Matter focusing on the development of engineered protein nanocages for the delivery of molecular cargoes to mitochondria.

Responsibilities

Understand and convey material of a specialist or highly technical nature to the team or group of people through presentations and discussions
Prepare and deliver presentations on research outputs/activities
Publish high quality outputs, including papers for submission to peer reviewed journals and papers for presentation at conferences
Assist with the development of research objectives and proposals
Conduct individual and collaborative research projects

Requirements

Nice to have: mitochondrial genetics
Nice to have: nanotechnology
Nice to have: extracellular vesicle engineering

Skills

protein engineering AI-enabled protein design synthetic biology recombinant protein production biophysical characterization

Principal Scientist, Formulation & Drug Product Development

Denali Therapeutics · Posted Sep 10, 2026

Open

South San Francisco, California, United States
On-site
Full-time · Principal
$159K–$207K per year
10+ years

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Serve as a formulation and drug product process development lead for a growing portfolio of protein biologics, providing technical formulation and drug product expertise across the development lifecycle.

Compensation

Salary Range: $159,000.00 to $207,000.00 . Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience.

Responsibilities

Independently drive formulation and drug product development activities for large molecule biotherapeutics
Design and execute formulation development studies to identify clinical and commercial formulation & dosage form, establish shelf life of DS & DP, assess in-use compatibility, and support comparability assessments
Develop stress comparability strategies to support process changes and scale-up
Oversee drug product process development activities as well as DP process characterization and process validation activities to support clinical and commercial manufacturing
Perform biophysical and biochemical characterization of protein therapeutics in the laboratory using chromatography-, capillary-, spectroscopy-based analytical methods

Requirements

PhD in Chemical Engineering
PhD in Pharmaceutical Sciences
PhD in Biophysics
PhD in Analytical Chemistry
BS or MS with commensurately greater directly relevant experience

Skills

Spring 2027 Co-Op, Structural Biology & Biophysics

Vertex Pharmaceuticals · Posted Nov 5, 2026

Open

Boston, Massachusetts, United States
On-site
Contract · Intern
$20–$35 per hour

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Support laboratory activities and research projects within the Structural Biology and Biophysics team, performing routine laboratory techniques, preparing reagents, and documenting experimental data.

Compensation

Full-time, paid co-op $20.00-35.00 USD/hour

Responsibilities

Support daily laboratory activities and research projects
Learn and perform routine laboratory techniques
Prepare buffers, reagents, samples, and assay plates
Support biochemical and biophysical assay activities
Collect, organize, and document experimental data

Requirements

Bachelor's or Master's degree in biochemistry, biology, chemistry, biotechnology, biophysics, molecular biology, pharmaceutical sciences or related field
Nice to have: prior experience in structural biology or biophysics
Nice to have: prior exposure to structural biology and/or biophysics through coursework, academic research, laboratory projects, internships, or scientific literature review
Nice to have: familiarity with nephelometry, turbidity measurements, microplate-based assays, plate readers, or laboratory automation

Skills

laboratory techniques protein purification

Spring 2027 Co-Op, Structural Biology & Biophysics

Vertex Inc. · Posted Nov 5, 2026

Open

Boston, Massachusetts, United States
On-site
Contract · Intern
$20–$35 per hour

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Support laboratory activities and research projects within the Structural Biology and Biophysics team, performing experimental work and data documentation.

Compensation

Full-time, paid co-op $20.00-35.00 USD/hour

Responsibilities

Support daily laboratory activities and research projects within the Structural Biology and Biophysics team.
Learn and perform routine laboratory techniques under the guidance of experienced scientists.
Prepare buffers, reagents, samples, and assay plates by following established procedures.
Support biochemical and biophysical assay activities, including nephelometry-based experiments used to evaluate properties such as sample solubility, aggregation, or precipitation.
Collect, organize, and document experimental data using laboratory notebooks, electronic systems, spreadsheets, and reports.

Requirements

Bachelor's or Master's degree in biochemistry, biology, chemistry, biotechnology, biophysics, molecular biology, pharmaceutical sciences, or a related scientific field
Nice to have: prior experience in structural biology, biophysics, or pharmaceutical research
Nice to have: prior exposure to structural biology and/or biophysics through coursework, academic research, laboratory projects, internships, or scientific literature review

Principal Scientist (m/f/d) Protein Engineering

Principal Scientist (m/f/d) Protein Engineering

Compensation

Responsibilities

Requirements

Skills

Benefits

PDRA

Responsibilities

Requirements

Skills

Principal Scientist, Formulation & Drug Product Development

Compensation

Responsibilities

Requirements

Skills

Spring 2027 Co-Op, Structural Biology & Biophysics

Compensation

Responsibilities

Requirements

Skills

Spring 2027 Co-Op, Structural Biology & Biophysics

Compensation

Responsibilities

Requirements

Skills

Benefits

Benefits

Benefits