- South San Francisco, California, United States
- $110K–$143K per year
- 3+ years
Compensation
Salary Range: $110,000.00 to $143,000.00 . Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Denali offers a competitive total rewards package, which includes a 401k, healthcare coverage, ESPP and a broad range of other benefits.
Responsibilities
- Design and execute in vivo and ex vivo studies that inform candidate progression, PK/PD modeling, and biomarker strategies
- Generate PK/PD data in preclinical models in partnership with Safety and DMPK scientists
- Perform molecular and biochemical assays, including RNA extraction, quantitative PCR, tissue sectioning, immunofluorescence, microscopy, and ELISAs
- Troubleshoot technical issues to keep experiments on schedule
- Evaluate oligonucleotide therapeutic candidates in CNS tissue-based models
Requirements
- PhD in Neuroscience, Cell Biology, Pharmacology, or a related scientific field
- Master’s degree and 3+ years of relevant experience in academia or pharmaceutical discovery/translational research