Senior Statistical Scientists provide experienced statistical, scientific and strategic support across assigned studies or indications, acting as a Study Statistician or Program Statistician.
Responsibilities
Responsible for the overall quality and the timely delivery of the statistical analyses for assigned studies in compliance with Sobi SOPs and regulatory requirements/guidelines
Provides leadership and oversight to in-house consultants and CRO statisticians
Supports the Program or Product Statistician in study design to meet project objectives and regulatory requirements
Develops or oversees the Statistical Analysis Plans (SAPs) and study-level statistical deliverables
Provides statistical input to study protocols, CRFs TFL shells or prototypes
Requirements
Bachelor of Science (BSc) in mathematical statistics, statistics or equivalent
Master of Science (MSc) in mathematical statistics, statistics or equivalent
PhD in mathematical statistics, statistics or equivalent
Lead biomarker strategy and execution for oncology clinical studies, driving translational research and clinical development.
Compensation
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
Responsibilities
Develop and drive clinical biomarker strategies, implementation, and execution for one or more programs
Develop clear and testable hypotheses for patient stratification/selection, pharmacodynamics, mechanism of action and resistance evidence from clinical trial samples
Responsible for biomarker elements in clinical protocols, biomarker analysis plans, regulatory submissions, investigator meetings, advisory boards and publications
Build productive relationships with team members, key opinion leaders, academic institutions and external partners
Partner with cross functional stakeholders to drive biomarker innovation at the product level as well as disease or modality level
A senior-level translational biology role in cardiovascular science responsible for evaluating existing targets, developing human-first strategies, identifying collaboration and business development opportunities, and guiding investment priorities.
Locations (2)
Stevenage, Hertfordshire, United Kingdom
Cambridge, Cambridgeshire, United Kingdom
Responsibilities
Provide scientific leadership to progress an existing preclinical and clinical cardiovascular portfolio by defining clear, human-relevant mechanistic hypotheses
Drive programs focused on cardiovascular disease biology, including vascular inflammation, endothelial dysfunction, fibrosis, remodeling, thrombosis, pulmonary vascular disease, heart failure-related mechanisms, and cardio-renal-metabolic disease pathways
Deliver translational strategies that incorporate human genetics, multi-omics, and reverse translation to strengthen target confidence and clinical relevance
Provide leadership on biomarker strategies, including target engagement, pharmacodynamic, disease activity, risk stratification, and patient-selection biomarkers