Principal Engineer, Pharmaceutical Development – Solid Oral Drug Products
Neurocrine Biosciences · Posted Nov 6, 2026
- San Diego, California, United States
- On-site
- Full-time · Principal
- $157K–$214K per year
- 4+ years
The Principal Engineer will serve as a senior technical leader and subject matter expert within Pharmaceutical Development, representing Technical Operations on cross-functional project teams focusing on late-stage development, process optimization, scale-up, and control strategy.
Compensation
The annual base salary we reasonably expect to pay is $156,900.00-$214,000.00. In addition, this position offers an annual bonus with a target of 30% of the earned base salary and eligibility to participate in our equity based long term incentive program.
Responsibilities
- Serve as a scientific subject matter expert in process engineering and pharmaceutical development of solid oral drug products
- Design and develop fit-for-purpose phase-appropriate processes (granulation, encapsulation, tablet compression, coating, spray drying, hot melt extrusion, etc.)
- Apply broad pharmaceutical development experience to identify process development risks (FMEA), evaluate experimental findings, and recommend strategies
- Provide independent scientific review of experimental designs, analytical data, electronic laboratory notebooks, technical reports, and regulatory documentation
- Provide technical oversight of CDMO partners
Requirements
- BS/BA degree in Chemistry
- BS/BA degree in Biochemistry
- BS/BA degree in Chemical Engineering
- MS/MA degree in Chemistry
- MS/MA degree in Biochemistry