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Investigative Safety Scientist/Toxicologist

Incyte Corporation · Posted Nov 11, 2026

Develop and apply innovative approaches to identify, characterize, and mitigate safety risks associated with small molecules and emerging modalities.

Develop and execute investigative toxicology strategies to elucidate mechanisms of toxicity and address potential safety liabilities.
Design and apply fit-for-purpose in vitro and ex vivo models and new approach methodologies (NAMs), including advanced 2D and 3D cultures, organoids, co-cultures, and organ-on-a-chip systems.
Evaluate and implement emerging technologies, automation, and high-throughput approaches to improve toxicity prediction and translational safety assessment.
Design and oversee in vivo investigative studies and integrate mechanistic, computational, and multi-omics data to identify safety liabilities, biomarkers, and translational relationships.
Collaborate with nonclinical safety scientists and cross-functional teams to translate scientific findings into actionable safety strategies and portfolio decisions.