Assay optimization jobs

Senior Scientist II R&D

Danaher · Posted Nov 9, 2026

Open

Fargo, North Dakota, United States
On-site
Full-time · Senior
5+ years

Senior Scientist II R&D

Danaher · Posted Nov 9, 2026

Open

Fargo, North Dakota, United States
On-site
Full-time · Senior
5+ years

AD/QC Analyst

Northway Biotech · Posted Oct 1, 2026

Open

Waltham, Massachusetts, United States
On-site
Full-time · Associate
3+ years

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Responsible for assay optimization, qualification, and validation, and technology transfer for proteins and other biomolecules.

Responsibilities

Assay optimization, qualification, and validation, and technology transfer for proteins and other biomolecules
Method development for identity, purity, aggregation status, charge isoforms, and potency using chromatography and electrophoresis
Support upstream and downstream process development in-process testing, drug substance/drug product release testing, and stability study testing
MS analysis of intact proteins and fragments generated by various enzyme digestion; peptide mapping analysis by LC-MS
Generate, manage, evaluate, and maintain data in a highly organized manner

Requirements

Bachelor’s or Master’s degree in Chemistry, Biochemistry, Pharmaceutical Sciences, or a related field
Nice to have: Enzyme protein and mAb intact mass analysis
Nice to have: Glycan analysis by LCMS
Nice to have: Understanding of mAb and protein molecular and biochemistry
Nice to have: Understanding of post-translational modifications

Skills

Assay optimization Assay qualification

Senior Scientist II R&D

Danaher Corporation · Posted Nov 9, 2026

Open

Fargo, North Dakota, United States
On-site
Full-time · Senior
5+ years

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Senior Scientist II, Analytical Method Development leading a small team focused on DNA, mRNA and lipid nanoparticle analytics within the R&D department.

Responsibilities

Lead a team focused on the design and development of new services and technologies such as mRNA, sgRNA, and LNPs
Lead the execution of experiments for bio-physical and chemical data analysis
Establish new site processes including preparation of a laboratory, installation/qualification of equipment, development of SOPs
Create detailed project reports and present findings and recommendations to both clients and senior management
Liaise between clients and analytical teams to facilitate the efficient transfer of knowledge

Requirements

PhD in biotechnology, biochemistry, or related discipline
MS with 7+ years of industry experience
BS with 10+ years of experience in related industry
Nice to have: CDMO experience
Nice to have: analytical method validation/qualification

Skills

development and optimization of biologics assay optimization experimental design

Senior Scientist, Biochemistry

PacBio · Posted Nov 6, 2026

Open

Menlo Park, California, United States
Hybrid
Full-time · Senior
$129K–$193K per year
2–5 years

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Senior Scientist to join an interdisciplinary team addressing biochemical challenges to advance DNA sequencing technology, contributing through hands-on laboratory experimentation, biochemical assay development, experimental design, and data analysis.

Compensation

Salary Range: $128,800.00 - $193,200.00

Responsibilities

Design and execute hypothesis-driven experiments that generate actionable insights to support sequencing chemistry development
Develop, optimize, and troubleshoot biochemical and biophysical assays, including single-molecule approaches, to characterize reaction performance and evaluate potential solutions
Design, source, and use custom DNA substrates and other specialized reagents for biochemical and biophysical experiments
Analyze and interpret experimental data, assess reproducibility, and present findings and conclusions in scientific and project meetings
Collaborate with scientists across disciplines to investigate technical challenges and develop solutions guided by biochemical insights

Requirements

PhD in Biochemistry, Biophysics, Molecular Biology, Chemistry, or a related field
Nice to have: Single-molecule fluorescence microscopy
Nice to have: DNA polymerases
Nice to have: Enzyme kinetics
Nice to have: DNA–protein interactions

Skills

Biochemical experimentation

Senior Scientist II R&D

Senior Scientist II R&D

Responsibilities

Requirements

Skills

Benefits

AD/QC Analyst

Responsibilities

Requirements

Skills

Senior Scientist II R&D

Responsibilities

Requirements

Skills

Senior Scientist, Biochemistry

Compensation

Responsibilities

Requirements

Skills

Benefits

Benefits