- Boston
- $195K–$239K per year
- 10+ years
Lead and manage a cross-functional team to develop shuttled oligonucleotide therapeutics, defining strategy, target product profiles, and advancing programs toward clinical testing.
Compensation
Base Salary Range: $195,000-239,000 This reflects the typical offer range for this role, based on experience, role scope, and internal equity. Final compensation decisions are made using a consistent leveling framework and consider the candidate’s experience, interview performance, and expected impact.
Responsibilities
- Build and lead a fit-for-purpose oligonucleotide therapeutic discovery team
- Lead 1-2 cross-functional drug discovery project teams
- Work with company leadership to prioritize high-value therapeutic targets
- Define best-in-class target product profiles
- Track advances in the field and provide strategic direction
Requirements
- PhD in a relevant field (chemistry, biochemistry, nucleic acid chemistry/biology, biophysics, molecular biology, pharmacology or related discipline)
- Nice to have: designing and interpreting in vitro and in vivo systems assessing oligonucleotide efficacy and safety
- Nice to have: engineering of optimized oligonucleotide conjugates
- Nice to have: linker discovery and bioconjugation optimization
- Nice to have: platforms for oligo design, synthesis, and screening