- Philadelphia, Pennsylvania, United States
- Full-time · Associate
- $21K–$110K per year
Conduct independent scholarly research and develop new methods and protocols in CAR T cell therapies targeting pediatric solid tumors.
Compensation
$20,800.00 - $110,400.00 Annually
Responsibilities
- Design, develop, and optimize genetically engineered CAR T cells for improved tumor targeting and persistence.
- Perform molecular cloning, lentiviral vector production, T cell transduction, and functional assays.
- Conduct in vitro experiments and use clinically relevant mouse models to evaluate CAR T cell efficacy and safety.
- Analyze experimental data, maintain accurate records in electronic laboratory notebooks, and prepare findings for publication and presentations.
- Collaborate with multidisciplinary teams including immunologists, clinicians, and bioinformaticians.
Requirements
- Doctorate
- Nice to have: Familiarity with CRISPR/Cas9 gene editing and advanced cell therapy development techniques.
- Nice to have: Experience with bioinformatics analysis, next-generation sequencing, or epigenetic profiling.
- Nice to have: Knowledge of pediatric solid tumor biology and translational cellular therapies.
- Nice to have: Demonstrated expertise in molecular biology techniques and cancer immunology.