Sr. Scientist, Electrochemical and Microarray DNA Synthesis
Atlas Data Storage · Posted Jul 6, 2026
- South San Francisco, California, United States
- On-site
- Full-time · Senior
- 2+ years
Lead scientific research and development of semiconductor-based DNA synthesis workflows, integrating chemistry, electrochemistry, and hardware systems.
Responsibilities
- Major contributor to the development and optimization of CMOS chip-based phosphoramidite DNA synthesis workflows.
- Develop and optimize electrochemical DNA synthesis protocols, including chip handling, hardware configuration and software integration, and chemistry process to improve synthesis efficiency and fidelity.
- Execute rigorous failure-mode analysis to systematically identify, diagnose, and resolve multi-variable root causes across hardware, fluidics, surface chemistry, phosphoramidite chemistry and electrochemistry.
- Collaborate with engineering and synthesis teams to build and iterate prototype testbeds, integrating chemistry, fluidics, and hardware systems.
- Operate NGS-based analytical pipelines for quality assessment of oligonucleotide pools.
Requirements
- PhD in Chemistry, Organic Chemistry, Chemical Engineering or a closely related field
- Master's in Chemistry, Organic Chemistry, Chemical Engineering or a closely related field
- Nice to have: oligonucleotide microarray or pool synthesis
- Nice to have: NGS workflows and data analysis
- Nice to have: DNA chip technologies and electrochemistry