- Seattle, Washington, United States
- Full-time
- $99K–$122K per year
- 4+ years
Research Scientist/Engr 4
Compensation
Pay Range Minimum: $99,444.00 annual Pay Range Maximum: $122,124.00 annual
Responsibilities
- 20% Structure-based and machine-learning immunogen design for protein subunit and mRNA vaccines based on viral surface glycoproteins (construct design, recombinant expression in mammalian cells, purification, and stability assays)
- 20% Characterize protein antigenicity (binding assays using ELISAs, SPR and biolayer interferometry to evaluate binding kinetics and affinity of antibodies or designed proteins)
- 15% Perform structural studies (high-throughput cryo-electron microscopy of subunit vaccines as well as of complexes between viral glycoproteins and monoclonal and polyclonal antibodies as well as X-ray crystallography)
- 10% Design and execution of virology assays
- 10% Analysis of the data to help determining the research strategy
Requirements
- Master's Degree in Biochemistry