Leading a wet-lab team to advance basic discovery and translational science programs in oncology, while serving as the Lead Scientific and Biomarker Advisor for clinical development.
Responsibilities
Lead, direct, and work hands-on alongside a focused wet-lab team of Ph.D. scientists.
Drive basic studies to elucidate tumor biomarkers.
Design, optimize, and supervise experimental workflows including 3D cell culture systems, patient-derived organoids, and tissue explants.
Manage archival and prospective patient biospecimen processing (FFPE, fresh-frozen, core biopsies, and biofluids).
Oversee multiplex IHC/IF, confocal imaging, and digital spatial profiling.
The in vivo pharmacology Senior Scientist will participate in the Gene Therapy in vivo pharmacology lab to execute experiments in support of the discovery and optimization of novel therapeutic candidates for genetic medicines.
Compensation
Pay rate: $55-57/hr on w2
Responsibilities
Work with team leads to design and execute in vivo pharmacology experiments to characterize activity, distribution, and clearance of genetic medicines in rodent models
Assist in the development and characterization of novel in vivo models
Collaborate with cross-functional partners to ensure the translation from discovery to development
Provide written and verbal communication of work in study reports and team meetings
Keep and maintain accurate and timely documentation of all practical work
Requirements
B.S./M.S. in life sciences (e.g., biology, neuroscience, or related field)
Investigate cellular and molecular mechanisms regulating immune cell responses and interactions within tissue microenvironments, design and perform in vivo experiments, and develop innovative research projects to advance immune cell reprogramming.
Compensation
The New York City, NY base pay range for a new hire in this role is Postdoctoral Fellow = $93,000.00 & Scientist I = $120,000 - $150,000. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.
Responsibilities
Investigate the cellular and molecular mechanisms regulating immune cell responses and interactions within tissue microenvironments.
Design and perform in vivo experiments using mouse models.
Characterize immune cell differentiation, function, and interactions with other cells.
Apply advanced experimental approaches, including molecular biology, single-cell sequencing, spatial transcriptomics, and genetic perturbation technologies.
Develop and test hypotheses to understand how immune cells and local tissue environments reciprocally shape each other’s behavior and function.
Requirements
PhD in molecular biology, bioengineering, genetics, cell biology, immunology, or a related field.
The in vivo pharmacology Scientist/Senior Scientist/Principal Scientist will participate in the Gene Therapy in vivo pharmacology lab to execute experiments in support of the discovery and optimization of Client therapeutic candidates for genetic medicines.
Compensation
Pay Rate: $57.28/Hr on W2
Responsibilities
Work with team leads to design and execute in vivo pharmacology experiments to characterize activity, distribution, and clearance of genetic medicines in rodent models, including mice, rats, and immuno-compromised animals.
Assist in the development and characterization of Client in vivo models.
Collaborate with cross-functional partners (Preclinical, toxicology, PK/PD modelling) to ensure the translation from discovery to development.
Provide written and verbal communication of work in study reports and team meetings.
Keep and maintain accurate and timely documentation of all practical work: completion of electronic notebook in alignment with client procedure quality standards and Good Documentation Practices.
In vivo pharmacology Scientist/Senior Scientist/Principal Scientist will participate in the Gene Therapy in vivo pharmacology lab to execute experiments in support of the discovery and optimization of Client therapeutic candidates for genetic medicines.
Responsibilities
Work with team leads to design and execute in vivo pharmacology experiments to characterize activity, distribution, and clearance of genetic medicines in rodent models, including mice, rats, and immuno-compromised animals.
Assist in the development and characterization of Client in vivo models.
Collaborate with cross-functional partners (Preclinical, toxicology, PK/PD modelling) to ensure the translation from discovery to development.
Provide written and verbal communication of work in study reports and team meetings.
Keep and maintain accurate and timely documentation of all practical work: completion of electronic notebook in alignment with procedure quality standards and Good Documentation Practices.
Requirements
B.S./M.S. in life sciences (e.g., biology, neuroscience, or related field)
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