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Scientist, Protein Sciences

Systimmune · Posted Nov 4, 2026

Bothell, Washington, United States
On-site
Full-time · Entry
$90K–$115K per year
0–3 years

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Drive design, expression, and purification of recombinant antigens to support antibody discovery and engineering programs.

Compensation

The expected base salary range for this position is $90,000 - $115,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate’s level qualifications, experience, and skills.

Responsibilities

Design and clone antigen constructs using molecular biology techniques, including vector design, cloning strategies, and sequence verification.
Develop and optimize transient and stable mammalian expression systems (e.g., HEK293 or CHO) to produce secreted and cell-surface antigens.
Establish and execute purification workflows for recombinant proteins, including affinity, ion-exchange, and size-exclusion chromatography.
Troubleshoot expression and purification problems, adjusting constructs, culture conditions, and purification strategies as needed.
Establish and execute quality control for each antigen batch, including purity, identity, and homogeneity.

Requirements

PhD in Biochemistry
PhD in Molecular Biology
PhD in related field
Nice to have: antibody discovery
Nice to have: immunization

Skills

molecular biology recombinant protein purification

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