- Seattle, Washington, United States
- $65K–$80K per year
- 0–5 years
Support the development, qualification, and routine execution of analytical methods for RNA, lipids, lipid nanoparticles (LNPs), and related bioconjugates at our Seattle site.
Compensation
Salary range: $65,000 – $80,000 total compensation, including bonus, depending on experience and qualifications.
Responsibilities
- Prepare RNA, oligonucleotide, lipid, LNP, antibody, and bioconjugate samples for analytical testing according to established procedures and experimental plans.
- Perform HPLC/UHPLC analyses using UV and/or charged aerosol detection (CAD), including sample and standard preparation, instrument sequence setup, chromatogram review, peak integration, and initial data assessment.
- Support chromatographic methods for evaluating RNA purity, lipid identity and purity, lipid composition, residual components, and related product-quality attributes.
- Assist with preparative chromatography, fraction collection, sample tracking, and evaluation of purification fractions for RNA and related development projects.
- Support analytical method development, optimization, troubleshooting, and transfer under the guidance of senior scientists and the group lead.
Requirements
- Bachelor's degree in Chemistry, Analytical Chemistry, Biochemistry, Biology, Biotechnology, Pharmaceutical Sciences, or a related scientific discipline.
- Nice to have: mRNA
- Nice to have: circRNA
- Nice to have: oligonucleotides