Lead in vivo research on obesity and diabetes in the Cardiometabolic Research unit at Lilly, designing and executing rodent studies, analyzing data, and contributing to translational science.
Compensation
Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $66,000 - $171,600
Responsibilities
Design and run acute and chronic in vivo studies in rodent models of obesity
Perform rodent handling, dosing (including multiple routes of administration) and necropsy with tissue collection
Measure in vivo endpoints such as body weight, food intake, body composition, energy expenditure and glucose and insulin tolerance
Run molecular and biochemical assays on ex vivo samples, such as qPCR, Western blot, ELISA, etc.
Work independently and within a team-oriented lab and cross-functional project teams
Requirements
Bachelor's degree in biology, pharmacology, physiology or a closely related field
Nice to have: Masters degree
Nice to have: 2+ years hands on experience in vivo studies in rodent models of obesity or metabolic disease
Nice to have: Experience in the biopharmaceutical industry
Nice to have: Familiarity with ex vivo models of adipose tissue
The Pharmacist performs medication management activities to ensure safe, rational, and cost-effective therapy while maintaining compliance with applicable rules and standards.
Compensation
Competitive pay, incentives, referral bonuses and 403(b) with employer contributions
Responsibilities
Process orders and provide medication review for appropriateness, safety and efficacy during order processing
Ensure accurate preparation of compounded and non-compounded products
Oversee distributive functions of the pharmacy department to facilitate accurate and timely medication availability
Oversee pharmacy technicians and support personnel activities
Maintain responsibility and accountability for the security of pharmacy inventory
Prepares and dispenses medications and other pharmaceutical supplies, using standard professional procedures to fill written or verbal physician orders.
Responsibilities
Order verification
Pharmacokinetic monitoring and dosing
Attending emergent responses to prepare medications and recommend dosing
Clinical initiatives such as IV to PO interchanges
Seeking a highly motivated Ocular Research Scientist to support the discovery and preclinical development of innovative therapies for retinal diseases, focusing on ocular biology, retinal disease models, and translational research.
Responsibilities
Lead and participate in research efforts to discover, characterize, and validate novel approaches for extrahepatic siRNA and RNA editing activities, with a focus on ophthalmology targets.
Develop, optimize, and characterize ocular mouse models relevant to AMD including Geographic atrophy (dry AMD), neovascular or wet AMD, diabetic retinopathy and diabetic macular edema, retinal vascular leakage and neovascularization, inherited and rare retinal diseases, retinal inflammation, and neurodegeneration.
Establishment of ocular in vivo systems to screen siRNAs via ocular dosing and administration in rodents, including intravitreal, subretinal, topical, periocular, and systemic delivery, as appropriate for the study.
Perform animal monitoring, clinical observations, study scheduling, tissue collection, necropsy procedures, and sample processing in accordance with approved protocols.
Conduct detailed microdissection of ocular tissues, including isolation of the retina, RPE/choroid, optic nerve, vitreous, aqueous humor, and other relevant ocular compartments.
We are seeking a skilled, motivated, and versatile individual who can help build a highly collaborative, successful drug discovery and development team in the Obesity research group in Boston, focusing on anti-obesity therapeutics.
Compensation
The anticipated wage for this position is $72,000 - $189,200
Responsibilities
Perform and support in vivo pharmacology studies in rodent models, working under the direction of project scientists.
Implement study procedures with precision, collect and process biological samples, and document results accurately.
Perform rodent handling, blood collection, and dosing by subcutaneous (SC), oral (PO), and intraperitoneal (IP) routes.
Measure and record body weight, body composition, and food intake throughout the course of in vivo studies.
Collect tissues at study termination and complete downstream sample processing for analysis.
The Specialty Pharmacist – Immunoglobulin Therapy provides clinical pharmacy services for patients receiving IVIg and SCIg, along with other chronic care infusion therapies, through evaluation of physician orders, clinical management, dosing, and safety monitoring, and the safe, efficient dispensing of medications, supplies, and administration equipment.
Compensation
$63.00 - $80.00 an hour
Responsibilities
Manage clinical care, dosing, and safety monitoring for patients on IVIg and SCIg therapies
Provide clinical oversight for patients on other chronic care infusion therapies
Evaluate and verify physician orders and patient medication profiles
Monitor medication appropriateness, stability, and compatibility
Review and dispense medications, supplies, and administration equipment
Requirements
Bachelor’s degree required
PharmD or Master's degree from an accredited School of Pharmacy required
Nice to have: Immunoglobulin Certified Pharmacist (IGCP®) credential
Nice to have: knowledge of sterile compounding practices
Nice to have: knowledge of laminar airflow principles
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