
Senior Analog/Mixed-Signal Hardware Engineer, Single-Molecule Sensing Instrumentation
Flagship Pioneering, Inc. · Posted Nov 5, 2026
- Cambridge, Massachusetts, United States
- Full-time · Senior
- $108K–$176K per year
- 5+ years
Lead the design and development of complex, multilayer PCBs for advanced instrumentation systems, including low-noise, picoamp-level sensing electronics.
Compensation
The salary range for this role is $108,000 - $176,000.
Responsibilities
- Lead the design and development of complex, multilayer PCBs for advanced instrumentation systems
- Architect low-noise, mixed-signal circuit designs including analog front ends, power management, data acquisition, and embedded processing systems
- Collaborate with SW and HW engineers as well as external vendors to ensure seamless hardware–software integration and instrument development
- Develop and maintain comprehensive documentation including schematics, layout files, validation reports, and specifications
- Drive design reviews, design for manufacturability (DFM), and design for testability (DFT) best practices
Requirements
- B.S., M.S., or Ph.D. in Electrical Engineering or a related field
- Nice to have: experience with high-speed interfaces
- Nice to have: experience designing electronics for scientific instrumentation
- Nice to have: experience with FPGA-based systems
- Nice to have: experience with high-density interconnect (HDI) design