- Boston, Massachusetts, United States
- Full-time · Associate
- $72K–$189K per year
- 5+ years
Lead development and optimization of downstream purification processes supporting viral vector programs from research through preclinical development.
Compensation
$72,000 - $189,200
Responsibilities
- Lead development, optimization, and scale-up of downstream purification workflows for viral vectors.
- Design and implement purification strategies using Iodixanol and CsCl density gradient ultracentrifugation, affinity chromatography, ion-exchange chromatography (AEX/CEX), membrane chromatography, and polishing operations.
- Lead AKTA-based chromatography workflow development and process intensification initiatives.
- Develop scalable downstream platform approaches to support rapid material generation and process consistency across programs.
- Independently design experiments, analyze data, interpret results, and present technical conclusions to multi-functional teams and leadership.
Requirements
- Bachelor’s degree in biology, biochemistry, chemical engineering, biotechnology, or related scientific field
- Master’s/PhD
- Nice to have: CsCl and iodixanol ultracentrifugation
- Nice to have: Affinity chromatography
- Nice to have: Ion-exchange chromatography