Support the production of life-changing therapies in a state‑of‑the‑art viral vector facility, executing complex virus purification and filtration processes while ensuring GMP compliance.
Compensation
The compensation range for this role is $22.49 - $28.11 hourly annually depending on experience and qualifications.
Responsibilities
Prioritize manufacturing schedule requirements and execute daily manufacturing schedule
Troubleshoot equipment and processes in partnership with Manufacturing Science and Technology
Conduct analytical tests such as osmolality, pH, conductivity and filter integrity testing
Communicate problems and observations with management
Provide engineering support of manufacturing equipment and operations, manage projects, analyze process data, ensure regulatory compliance, and support process teams across Celltrion sites.
Compensation
This role is exempt and the anticipated compensation for this role is $87,000 - $150,000.
Responsibilities
Plan, coordinate, and execute projects supporting clinical and commercial manufacturing operations
Use historian data and other sources to extract and chart relevant process parameters
Analyze process data to identify solutions
Ensure regulatory compliance of equipment and process performance
Participate in Process Teams to verify process control
Requirements
Bachelor of Science in Chemical Engineering
Bachelor of Science in Mechanical Engineering
Bachelor of Science in related engineering discipline
Seeking an innovative Scientist in the Purification Development group developing downstream processes for mAbs, bispecifics, enzymes, recombinant proteins, Fc fusions, etc.
Compensation
The base compensation range for this role is $75,000-$80,000.
Responsibilities
Support the development, optimization, and validation of purification workflows as well as process transfers to and from client sites.
Develop appropriate tools and technologies to enable right at first pass scale-up and technology transfer.
Supporting multiple client projects in parallel for protein purification.
Work with senior leadership on developing downstream purification processes for client projects.
Generate ideas for continuous improvement and innovative internal capabilities.
Requirements
BS in Biological Sciences
MS in Biological Sciences
Nice to have: JMP statistics
Nice to have: DoE setup
Nice to have: Experience in managing or contributing to multiple projects
Lead development and optimization of downstream purification processes supporting viral vector programs from research through preclinical development.
Compensation
$72,000 - $189,200
Responsibilities
Lead development, optimization, and scale-up of downstream purification workflows for viral vectors.
Design and implement purification strategies using Iodixanol and CsCl density gradient ultracentrifugation, affinity chromatography, ion-exchange chromatography (AEX/CEX), membrane chromatography, and polishing operations.
Lead AKTA-based chromatography workflow development and process intensification initiatives.
Develop scalable downstream platform approaches to support rapid material generation and process consistency across programs.
Independently design experiments, analyze data, interpret results, and present technical conclusions to multi-functional teams and leadership.
Requirements
Bachelor’s degree in biology, biochemistry, chemical engineering, biotechnology, or related scientific field
Master’s/PhD
Nice to have: CsCl and iodixanol ultracentrifugation
Support the design, manufacturing and characterization of lipid nanoparticles for process development and scale-up.
Responsibilities
Support the design, manufacturing and characterization of lipid nanoparticles (LNPs) for screening critical process parameters (CPPs) and critical material attributes (CMAs) that impact critical quality attributes (CQAs).
Support the design and execution of a wide range of experiments including DoEs to advance LNP technology and process development.
Participate in defining equipment specification/selection, draft procedures and recommended operating parameters/ranges.
Write protocols, perform experiments, organize and analyze data, interpret results, record experiments in an electronic lab notebook, and summarize work in presentations and technical reports.
Assist in ordering supplies, making reagents, and maintaining a safe and high-performing laboratory.
Requirements
Bachelor’s/Master’s degree in chemical engineering, bioengineering, chemistry, pharmaceutical sciences, or another related field
Nice to have: Experience with lipid nanoparticle formulations and analytical characterization methods
Engineer to support lipid nanoparticle (LNP) process development, scale‑up, and characterization for gene editing therapies.
Compensation
Pay Rate: $65.00 – $68.00/hr on W2 (Without Benefits)
Responsibilities
Support the design, manufacturing and characterization of lipid nanoparticles (LNPs) for screening critical process parameters (CPPs) and critical material attributes (CMAs) that impact critical quality attributes (CQAs).
Support the design and execution of a wide range of experiments including DoEs to advance LNP technology and process development.
Participate in defining equipment specification/selection, draft procedures and recommended operating parameters/ranges
Write protocols, perform experiments, organize and analyze data, interpret results, record experiments in an electronic lab notebook, and summarize work in presentations and technical reports
Assist in ordering supplies, making reagents, and maintaining a safe and high-performing laboratory
Requirements
Bachelor's/Master's degree in chemical engineering, bioengineering, chemistry, pharmaceutical sciences, or another related field
Nice to have: lipid nanoparticle formulations and analytical characterization methods
Support the development and advancement of lipid nanoparticle (LNP) formulations for the delivery of nucleic acid therapeutics.
Compensation
The salary range for this role is $74,000 - $107,300.
Responsibilities
Design, formulate, produce, and characterize LNPs to support preclinical research for internal platform and external partnerships.
Execute LNP production across a range of process scales, from small-scale formulation and process optimization through larger-scale production.
Operate and develop processes using relevant LNP manufacturing and process-development equipment, including mixers, pumping systems, tangential flow filtration (TFF), and related technologies.
Troubleshoot formulation and process challenges and contribute to the optimization and continuous improvement of LNP production processes.
Collaborate closely with scientists and cross-functional teams to design experiments, interpret results, and advance program objectives.
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