R&D Scientist I for Gas Chromatography lab (GC section) responsible for handling advanced analytical instruments, managing daily operations, and interacting with global development teams.
Responsibilities
Hands on operation, analysis, calibration & interpretation of results using wide range of Gas chromatography system including conventional GC (TCD/FID/SCD), GC MS, Analyzer like SIMDIST, Reformulyzer, DHA.
Provide basic troubleshooting for these instruments.
Design, optimize, and validate new GC and GC-MS (Gas Chromatography-Mass Spectrometry) methods for complex sample matrices.
Compliance with site HSE policies and procedures and adopt HSE requirements for safe laboratory operations.
Keep abreast of new analytical method /advanced characterization technique related to complex hydrocarbon molecules.
Requirements
MSc in Analytical/ Organic Chemistry
Nice to have: Refinery / Petrochemicals experience
The Process Scientist will join a lean R&D team to define experimental processes and develop chemistries, moving work from bench-scale discovery to real-world application for textile recycling.
Compensation
Competitive and experience-guided compensation, including equity
Responsibilities
Develop new chemistries to purify and upgrade various blended polyester wastes
Design and run lab-scale chemical reactions
Analyze intermediates and products using appropriate analytical techniques
Critically evaluate results, identify and troubleshoot challenges, and plan experiments
Review relevant literature to inform new synthesis approaches
Provide scientific leadership for analytical development (AD) supporting next-generation mRNA-LNP-based in vivo CAR-T therapies within the Advanced Delivery Systems (ADS) organization.
Compensation
The anticipated wage for this position is $141,000 - $231,000. Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance).
Responsibilities
Serve as the technical lead and group leader for the separation science function within Analytical Development, defining and executing chemistry assay strategy and roadmap for RNA-LNP-based programs.
Lead end-to-end development, optimization, pre-qualification, and technical transfer of chemistry assays across separation platforms (e.g., IP-UPLC, RP-UPLC, CGE, LC-MS, SEC, SEC-MALS, IEX) to characterize and quantify mRNA, protein, and lipid components of drug product.
Represent the separation science function on cross-functional project teams and in technical review settings, and act as the primary analytical SME.
Ensure assay data, methods, and practices comply with ICH guidelines and industry best practices for cell and gene therapies.
Design, develop, and execute stability-indicating methods and forced-degradation studies to support product characterization, shelf-life determination, and ongoing stability programs.
Requirements
PhD in chemistry
PhD in biochemistry
MS in chemistry
MS in biochemistry
Senior Advisor, Separation Science — Analytical Development
Provide scientific leadership for analytical development supporting next-generation mRNA‑LNP‑based in vivo CAR‑T therapies within the Advanced Delivery Systems organization.
Compensation
$141,000 - $231,000
Responsibilities
Serve as the technical lead and group leader for the separation science function within Analytical Development, defining and executing chemistry assay strategy and roadmap for RNA‑LNP‑based programs.
Lead end‑to‑end development, optimization, pre‑qualification, and technical transfer of chemistry assays across separation platforms to characterize and quantify mRNA, protein, and lipid components of drug product.
Represent the separation science function on cross‑functional project teams and in technical review settings, and act as the primary analytical SME.
Ensure assay data, methods, and practices comply with ICH guidelines and industry best practices for cell and gene therapies.
Design, develop, and execute stability‑indicating methods and forced‑degradation studies to support product characterization, shelf‑life determination, and ongoing stability programs.
Process ScientistMacroCycle Technologies · Cambridge, US
Senior Advisor, Separation Science — Analytical DevelopmentLilly · Boston, US