Senior Research Associate / Associate Scientist in a nonclinical biotech research setting, responsible for designing, optimizing, and executing cell-based assays to evaluate engineered tRNA therapeutics.
The salary range for this role is $81,000 - $126,500.
- Design, optimize, qualify, validate, and implement cell-based assays that support early-stage discovery efforts, selection of new indications, and advancement of lead candidates into IND-enabling studies
- Execute in vitro assays and process in vitro and in vivo samples to support nonclinical studies, following approved protocols and SOPs
- Conduct biochemical assays to support the development of clinical and nonclinical biomarkers
- Document experiments accurately and promptly in the electronic laboratory notebook (ELN), ensuring data integrity, traceability, and complete records
- Perform mammalian cell culture, cell line characterization, and cell line development, including DNA/RNA delivery by transfection, transduction, electroporation, or LNP-based methods
- BS or MS in biology, biochemistry, pharmacology, or a related field
- Nice to have: RNA therapeutics
- Nice to have: mRNA
- Nice to have: siRNA
- Nice to have: antisense oligonucleotides
Senior Research Associate / Associate Scientist, NonclinicalFlagship Pioneering, Inc. · Cambridge, US