Ephla Bio is looking for a bioinformatician to turn biological and experimental data into insights that guide therapeutic development. Build reproducible analysis pipelines, interpret complex datasets, and apply statistical methods to target prioritization.
Locations (3)
Toronto, Ontario, Canada
San Francisco Bay Area, California, United States
New York, New York, United States
Responsibilities
Build and validate workflows from tumor/normal sequencing (WES/WGS, RNA-seq) through QC, somatic variant calling, VAF and clonality analysis (truncal vs. subclonal, adjusted for purity and copy number), HLA typing, expression quantification, and reporting.
Analyze HTS data and other large-scale screens. Integrate them with public datasets (e.g. immunopeptidomics) and turn patterns into testable hypotheses.
Assess assay quality, batch effects, and biological variability. Benchmark methods, validate findings against independent datasets or experimental results, and communicate uncertainty early.
Combine assay results, sequence annotations, and relevant biological evidence to rank candidates and explain the rationale for experimental follow-up.
Design experiments with lab scientists (scale, controls, data priorities), turn predictions into testable candidates, and feed results into the next round.
Provide independent scientific and quality oversight for biomarker assay development, validation, implementation, and ongoing performance across multiple technology platforms.
Compensation
Salary Range (annually) $128,600.00 - $210,000.00
Responsibilities
Provide independent scientific and quality oversight for biomarker assay development, validation, implementation, and ongoing performance across multiple technology platforms.
Review and approve assay-development scopes of work, analytical validation plans, quality-monitoring plans, final validation reports, and biomarker analytical reports.
Define fit-for-purpose validation strategies and design pilot studies to identify and control preanalytical variables that may affect assay performance.
Partner with Global Clinical Operations and external laboratories to ensure assays are properly validated and implemented for clinical sample testing.
Conduct technical assessments and site visits as needed to evaluate analytical performance, operational rigor, scientific quality, and readiness to meet clinical-study needs.
Requirements
Ph.D.
M.D.
or comparable advanced degree in a relevant scientific discipline
The Field Applications Scientist is responsible for working with scientists to understand their application requirements and help to adapt their workflows to the outstanding capabilities of our liquid handling and automation product portfolio.
Locations (9)
Seattle, Washington, United States
Portland, Oregon, United States
Salt Lake City, Utah, United States
Wyoming, United States
Idaho, United States
Research Associate
University of British Columbia · Posted Nov 6, 2026
Lead and execute research projects focused on developing non-invasive biomarkers for diagnosing and predicting outcomes in cardiothoracic transplantation
Compensation
Salary is $79,872.00 per annum plus benefits.
Responsibilities
Lead and execute research projects focused on developing non-invasive biomarkers for diagnosing and predicting outcomes in cardiothoracic transplantation
Conduct multi-omics research (metabolomics, proteomics, genomics) to identify metabolic signatures and pathways associated with transplant rejection and post-transplant outcomes
Investigate the pathogenesis and biomarkers of long COVID, contributing to therapeutic strategies that address SARS-CoV-2 persistence, immune dysregulation, chronic inflammation, vascular injury, hypercoagulability, and multi-organ involvement
Collaborate with clinicians, bioinformaticians, and public health researchers to apply precision medicine approaches, including the development of real-time diagnostic tools for clinical use
Coordinate and develop grant applications to secure research funding
Seeking a highly motivated Research Scientist with a background in cardiothoracic transplantation, biomarker discovery, and multi-omics research to lead projects on improving diagnostic accuracy and predicting transplant outcomes.
Compensation
Salary is $79,872.00 per annum plus benefits.
Responsibilities
Lead and execute research projects focused on developing non-invasive biomarkers for diagnosing and predicting outcomes in cardiothoracic transplantation
Conduct multi-omics research (metabolomics, proteomics, genomics) to identify metabolic signatures and pathways
Investigate the pathogenesis and biomarkers of long COVID
Collaborate with clinicians, bioinformaticians, and public health researchers to apply precision medicine approaches
Coordinate and develop grant applications to secure research funding
Requirements
MD
MSc
Nice to have: academic recognition
Nice to have: awards
Nice to have: oral presentations at international conferences
The Postdoc will work on the ERC Starting Grant-project 'LIVER-CIRCUITS', focusing on investigating how the nervous system controls chronic liver disease and liver cancer. The role involves mapping liver innervation, manipulating neural circuits using various experimental approaches, and integrating advanced omics (scRNA-seq, spatial transcriptomics) with translational studies on human samples.
Compensation
Die Vergütung erfolgt nach den Eingruppierungsvorschriften des Tarifverrages für den öffentlichen Dienst (TV-L) und ist bei Vorliegen der persönlichen Voraussetzungen in der Entgeltgruppe E13 möglich sowie Jahressonderzahlung.
Responsibilities
Kartierung der sympathischen, sensorischen und autonomen Innervation der Leber sowie der Mikroumgebung von Tumoren
Analyse der Regulation von Immun-, Stromal-, Gefäß- und Epithelzellzuständen durch neuronale Signale
The Vice President, Data Science provides senior leadership for Caris’ AI-driven clinical insights and predictive modeling initiatives. This role leads the development of novel AI signatures leveraging Caris’ large-scale clinico-genomic database to identify molecular characteristics of disease.
Responsibilities
Define and execute the strategy for AI-driven clinical insight and molecular signature development across Caris’ molecular profiling platforms.
Identify clinically relevant questions where advanced analytics can deliver prognostic or predictive insights.
Oversee development of AI signatures integrating genomic, transcriptomic, proteomic, and clinical outcomes data.
Establish governance and standards for model development, validation, documentation, and lifecycle management.
Collaborate with Regulatory and Clinical Development teams to ensure appropriate validation and evidence generation.
Requirements
PhD in Data Science, Biostatistics, Computer Science, Biomedical Engineering, or a related field
Nice to have: experience working in regulated clinical laboratory environments (CAP/CLIA)
Nice to have: cloud computing platforms
Nice to have: large-scale data infrastructures
Nice to have: translating advanced analytics into physician-facing clinical products
The annual salary range OR the hourly range for this role is $95,000.00 - $115,000.00.
Responsibilities
Provide applications support across multiple scientific subject areas, including drug discovery and genomics.
Understand the scope of customer projects and be able to build, adapt, implement, and optimize liquid handling and automation protocols to improve customer workflows.
Provide customer training and support; maintain positive customer relations.
Support sales targets by partnering with the commercial team to provide high-level scientific and technical expertise.
Troubleshoot and diagnose technical problems and serve as a liaison with service and internal customer support teams as needed.
Requirements
Bachelor’s degree in Life Science or related field of study
Nice to have: Advanced programming of laboratory automation workflows
Nice to have: Technical or application support within a Life Science company
Biology & Bioinformatics Research Specialist (MSc/PhD)NewGramian Consulting Group · Remote, US+10 more
Research Fellow - Department of Cancer and Genomic Sciences - 108203 - Grade 7University of Birmingham · Birmingham, United Kingdom