- Indianapolis, Indiana, United States
- On-site
- Full-time · Associate
- $31–$34 per hour
- 2+ years
The Biochemist III will support the early molecule discovery team by designing and implementing biochemical and biophysical assays to support hit identification, hit triage, and mechanism of action characterization across diverse molecular targets.
Compensation
Compensation Range: $31.00-$34.00 per hour (e.g., the job posting is not necessarily reflective of actual compensation that may be earned, and actual compensation is subject to variation due to such factors as location, education, experience, and skillset).
Responsibilities
- Design, develop, and validate biochemical and biophysical assays for hit identification, hit triage, and mechanism of action characterization.
- Perform biochemical assays using TR-FRET, fluorescence polarization (FP), AlphaLISA/AlphaScreen, luminescence, and ELISA formats.
- Prepare assay reagents, protein dilutions, substrate stocks, and compound serial dilutions.
- Execute enzyme activity assays, protein–protein interaction assays, and binding assays with guidance.
- Run assays in 384- and 1536-well microplate formats.
Requirements
- Master’s Degree in Chemistry, Biochemistry or closely related field