Conduct research in lung and nasal immunity against respiratory viruses, manage experiments, analyze data, assist manuscript and grant writing, maintain lab equipment, and attend scientific conferences.
Responsibilities
Conduct research experiments in the field of Lung and Nasal Immunity Against Respiratory Viruses, T Cell Memory, Aged Immune Responses.
Collect and analyze data, including periodical/literature search and utilizing specialized skills in related fields to analyze the collected data.
Participate/assist in manuscript writing for publication in scientific journals and/or presentations. May also assist in grant writing.
Lab maintenance, including equipment maintenance and ordering of supplies as needed.
Other duties as assigned, which may include attending Scientific Conferences and Meetings.
Requirements
Doctoral Degree (or foreign equivalent) in Immunology or a closely related field
Scientist II in the gRED Cell Therapy Department supporting in vivo cell therapy research, focusing on lentiviral vector production, characterization, and assay development.
Responsibilities
Execute and optimize research-scale lentiviral vector production workflows
Produce and characterize research-grade lentiviral vectors for in vitro evaluation and preclinical studies
Develop, optimize, and execute molecular and cell-based assays to assess vector quality, titer, gene delivery, CAR expression, and functional activity
Perform primary human cell culture and engineering studies to support delivery platform evaluation
Apply flow cytometry to assess transduction efficiency, CAR expression, and cell phenotype
Requirements
Bachelor's or Master's in Immunology, Virology, Molecular Biology, Bioengineering, Cell Biology or related discipline
PhD in Immunology, Virology, Molecular Biology, Bioengineering, Cell Biology or related discipline
Nice to have: suspension-based lentiviral vector production
Laboratory-based scientist conducting in vitro and ex vivo experiments, developing assays, and supporting toxicology research.
Compensation
Pay Rate: $32.58 – $46.79/hour + Benefits
Responsibilities
Culture, maintain, and expand primary cells and immortalized cell lines for in vitro screening and research studies.
Perform laboratory assays to evaluate cell viability, cytotoxicity, and cellular metabolic changes.
Conduct experiments using techniques such as Luminex, ELISA, gene expression analysis, high-content screening, confocal microscopy, and flow cytometry.
Capture and analyze cell culture images using high-content imaging technologies.
Work with cells from various tissue types, including immune cells, blood, liver, vascular, ocular tissues, and immortalized cell lines.
Requirements
Bachelor's degree (BS/BA) in Pharmacology, Pharmaceutical Sciences, Biology, Bioengineering, Chemistry, Physiology, or a related scientific discipline.
Scientist II in the gRED Cell Therapy Department supporting in vivo cell therapy research with a focus on lentiviral vector production and analytical assay development.
Responsibilities
Execute and optimize research-scale lentiviral vector production workflows
Produce and characterize research-grade lentiviral vectors for in vitro evaluation and preclinical studies
Develop, optimize, and execute molecular and cell-based assays to assess vector quality, titer, gene delivery, CAR expression, and functional activity
Perform primary human cell culture and engineering studies to support evaluation of delivery platforms for in vivo cell therapy applications
Apply flow cytometry to assess transduction efficiency, CAR expression, and cell phenotype
Requirements
Bachelor's or Master's in Immunology, Virology, Molecular Biology, Bioengineering, Cell Biology or related discipline
PhD in Immunology, Virology, Molecular Biology, Bioengineering, Cell Biology or related discipline
The successful applicant will be an experienced and enthusiastic research technician working in the field of animal research, overseeing and implementing a portfolio of in vivo studies for multiple cancer projects.
Compensation
Salary: £32,722 to £33,662 with progression to £35,302 per annum
Responsibilities
Oversee and implement a portfolio of in vivo studies for multiple cancer projects
Work with PIs to deliver state of the art study design, innovation, and delivery to underpin cancer research
Provide expertise in area of in vivo rodent cancer modelling, including orthotopic PDX modelling and in vivo imaging
Develop improved animal models and methods for non-invasive assessment of malignant disease location and progression
Ensure provision of appropriate resources and compliance with regulatory frameworks
Requirements
BTEC HNC / HND
A’ level
broad work experience acquired through vocational training
Nice to have: professional registration with an accredited professional body (including HEA)
Laboratory Director to lead and grow Genetics/Genomics and Flow Cytometry programs, providing strategic and operational leadership and ensuring quality and regulatory compliance.
Responsibilities
Lead and grow Genetics/Genomics and Flow Cytometry programs
Partner with clinicians, pathologists, and organizational leaders
Drive innovation and ensure quality and regulatory compliance
Advance patient care
Manage multi-facility functions
Requirements
bachelor’s degree in business, healthcare administration or related field
Nice to have: Additional related education and/or experience