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1–2 jobs· newest first

Senior Computational BiologistNew
Probably Genetic · San Francisco, US
Hybrid · Full-time · Senior
Per Diem Bioinformatics Specialist III Barakat Research Group
Mass General Brigham · Boston, US
$94K–$137KHybrid · Temporary · Senior

+10K new in the last hour

Senior Computational Biologist

Probably Genetic · Posted Nov 9, 2026

San Francisco, California, United States
Hybrid
Full-time · Senior
4+ years

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The Senior Computational Biologist will own bio data pipelines and interpretation end-to-end, taking data from QC through to target hypotheses and collaborating with ML researchers to support target discovery.

Compensation

competitive salaries, comprehensive benefits, and meaningful early-stage equity

Responsibilities

Bio data processing and QC: take over, improve and fully automate our in-house pipeline for genetic data analysis
Run power analyses and use your insights to inform which phenotypes and indications we prioritize, how we scale our database, and which data modalities we collect
Prove our data and pipelines recover known gene-phenotype associations and approved target-indication pairs, and replicate them against public resources
Conduct association and causal gene mapping in a selected indication, incl. via rare variant burden tests, colocalization tests, and Mendelian randomization
Partner with ML researchers on data preparation, multi-modal integration and shared evaluation

Requirements

PhD in statistical genetics, computational biology, bioinformatics, or similar
Nice to have: target discovery
Nice to have: human genetics
Nice to have: biotech
Nice to have: biopharma

Skills

Python Snakemake Genetic data analysis Genomic data analysis Machine learning fluency gnomAD GTEx Open Targets ClinVar cloud-scale genomic data resources

Benefits

competitive early-stage equity grants
Flexible Time off
Parental Leave (12 weeks)
Health Benefits (medical, dental, vision, therapy, FSA, and 401k)
Company-sponsored team lunch

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Per Diem Bioinformatics Specialist III Barakat Research Group

Mass General Brigham · Posted Nov 4, 2026

Boston, Massachusetts, United States
Hybrid
Temporary · Senior
$94K–$137K per year
5–7 years

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Responsible for leading complex bioinformatics projects and overseeing data analysis workflows.

Compensation

$93953.60 - $136739.20/Annual

Responsibilities

Design and apply novel computational methods/bioinformatics algorithms, machine learning models for building data models and tools using various software and statistical tools to aid in the analysis and interpretation of genetic data, clinical data, and images.
Collaborate with other teams, stakeholders, and external partners on large-scale projects.
Contribute to the development of bioinformatics strategies and research plans.
Mentor and train junior analysts or team members.
Design, maintain, and troubleshoot data processing/software pipelines and data architecture using various computational tools.

Requirements

Bachelor's Degree
Master's Degree preferred

Skills

bioinformatics algorithms machine learning models statistical tools genetic data analysis

clinical data analysis

data architecture

experimental design

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