Referso Jobs

Engineer III, Advanced Extraction Process Development

Entegris · Posted Nov 9, 2026

Open

Colorado Springs, Colorado, United States
On-site
Full-time · Senior
$100K–$125K per year

Engineer III, Advanced Extraction Process Development

Entegris · Posted Nov 9, 2026

Open

Colorado Springs, Colorado, United States
On-site
Full-time · Senior
$100K–$125K per year

Principal Scientist – Oligonucleotide & AOC Analytical Chemistry

Atrium Therapeutics · Posted Nov 6, 2026

Open

San Diego, California, United States
Full-time · Senior
$185K–$205K per year
8+ years

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Lead analytical characterization of antibody-oligonucleotide conjugates (AOCs) and develop phase-appropriate analytical methods for drug substance, product, and intermediates.

Compensation

The base salary range for this role is $185,000-$205,000. The final compensation will be commensurate with such factors as relevant experience, skillset, internal equity and market factors.

Responsibilities

Lead efforts to build internal analytical capabilities and laboratory infrastructure.
Develop, optimize, qualify, and transfer analytical methods for AOCs, oligonucleotide intermediates, and related materials.
Design and execute forced-degradation and development stability studies; elucidate degradation pathways for both the antibody and oligonucleotide components.
Serve as analytical lead and provide in-process and release-type analytical testing of oligonucleotides and conjugates in support of discovery, process development, and GLP studies.
Partner with oligonucleotide and AOC bioconjugation teams to develop analytical methods to characterize and quantify process intermediates and impurities.

Requirements

Ph.D. in analytical chemistry, biochemistry, chemistry or a related field
M.S. with 12+ years
B.S. with 14+ years

Skills

HPLC/UHPLC (SEC, HIC, IEX, IP-RP)

Senior Scientist – Upstream Process Development (Temporary Maternity Cover)

AstraZeneca · Posted Nov 4, 2026

Open

Cambridge, Cambridgeshire, United Kingdom
On-site
Temporary · Senior

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A Senior Scientist role responsible for hands-on scientific delivery of upstream cell culture process activities supporting biologics pipeline, focusing on process development, scale-up, and technology transfer within a matrix environment.

Responsibilities

Deliver assigned upstream process development activities across CMC cycles
Perform and contribute to the design and interpretation of mammalian cell culture studies using CHO cells, including cryopreservation, revival, inoculum expansion, fed-batch and perfusion processes
Operate high-throughput and bench-scale bioreactor platforms including ambr systems and stirred-tank bioreactors
Apply Design of Experiments (DoE) and multivariate analysis to identify process drivers
Assess cell growth, viability, metabolism, productivity, and culture stability

Requirements

Biochemical engineering
Bioprocessing
Biotechnology
Biology
Nice to have: PhD or Master's degree

Skills

Mammalian cell culture Upstream process development CHO cell culture Aseptic technique

Senior Scientist – Upstream Process Development (Temporary Maternity Cover)

AstraZeneca · Posted Nov 4, 2026

Open

Cambridge, Camshire, United Kingdom
On-site
Temporary · Senior

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Responsible for the hands-on scientific and technical delivery of upstream mammalian cell culture process development activities supporting AstraZeneca’s biologics pipeline.

Responsibilities

Deliver assigned upstream process development activities across CMC development cycles.
Perform and contribute to the design and interpretation of mammalian cell culture studies using CHO-based systems.
Execute cryopreservation, revival, inoculum expansion, fed-batch and perfusion processes.
Operate high-throughput and bench-scale bioreactor platforms including ambr systems and stirred-tank bioreactors.
Apply Design of Experiments, multivariate analysis, and statistical approaches to identify process drivers.

Requirements

BSc/MSc/PhD in biochemical engineering
bioprocessing
biotechnology
biology
related scientific discipline

Skills

mammalian upstream process development CHO cell culture aseptic cell culture bioreactor-system operation Design of Experiments (DoE)

Engineer III, Advanced Extraction Process Development

Engineer III, Advanced Extraction Process Development

Compensation

Responsibilities

Requirements

Skills

Benefits

Principal Scientist – Oligonucleotide & AOC Analytical Chemistry

Compensation

Responsibilities

Requirements

Skills

Senior Scientist – Upstream Process Development (Temporary Maternity Cover)

Responsibilities

Requirements

Skills

Senior Scientist – Upstream Process Development (Temporary Maternity Cover)

Responsibilities

Requirements

Skills

Benefits

Design-Expert jobs

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Compensation

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