Scientist I or Scientist II in Biochemistry and Reagents R&D, responsible for protein purification, library preparation, and workflow optimization.
Compensation
$97,400.00 - $168,000.00
Responsibilities
Execute protein expression and purification protocols, including FPLC-based and plate-based high-throughput preparations, in partnership with the group's protein purification lead.
Prepare HiFi sequencing libraries and run sequencing chemistry experiments on PacBio platforms.
Execute targeted enrichment workflows following PacBio protocols, including testing new guide RNA designs.
Learn new protocols quickly and move between projects and workflows as priorities change, while maintaining high quality and reproducibility.
Perform QC on nucleic acids and proteins (e.g., Qubit, Femto Pulse or Bioanalyzer, SDS-PAGE) and evaluate results against defined performance metrics.
Requirements
PhD in Biochemistry, Molecular Biology, Biophysics, Chemistry, Bioengineering, or a related field
Nice to have: familiarity with long-read sequencing (PacBio HiFi or Oxford Nanopore) or CRISPR-based targeted sequencing workflows
Nice to have: computational skills in Python or R
Nice to have: protein structure visualization (e.g., Chimera, PyMOL)
Nice to have: laboratory database management or LIMS experience
Senior Scientist to serve as the protein purification subject-matter expert within the Biochemistry and Reagents R&D group.
Compensation
$128,800.00 - $193,200.00
Responsibilities
Build, run, and continuously improve purification pipelines for nucleic acid–modifying enzymes at multiple research scales.
Serve as the group's subject-matter expert on protein expression and purification; advise colleagues on construct design, expression host, affinity tags, and purification strategy.
Develop expression and purification strategies for challenging targets, including poorly soluble proteins, multi-subunit complexes, and novel homologs, where standard protocols fall short; evaluate alternative strategies side by side to maximize yield, activity, and purity.
Design and execute high-throughput 24- to 96-plex expression and purification campaigns on lab automation platforms to screen enzyme variants and homologs in parallel.
Perform targeted individual purifications on ÄKTA FPLC systems using affinity, ion-exchange, size-exclusion, and other chromatography methods.
Requirements
PhD in Biochemistry, Molecular Biology, Biophysics, Chemistry, Bioengineering, or a related field
Nice to have: industry R&D experience in biotechnology, life science tools, or enzyme and reagent development
Nice to have: single-molecule biochemistry or biophysics
Postdoctoral Research Fellow - Center for Discovery & Innovation
Integral part of an antibody development team focusing on performance and specificity using innovative molecular, protein, biochemical and cell biology methods.
Responsibilities
Meticulous experimental planning and execution to meet program goals.
Timely record keeping of results into data sheets and laboratory note-books.
Regular mining of literature and keeping oneself up to date with developments in field of antibody development.
Compilation and presentation of data in written and oral formats. Active participation in team meetings.
Integral part of an antibody development team focusing on performance and specificity using innovative molecular, protein, biochemical and cell biology methods.
Compensation
We offer competitive remuneration, annual incentive plan bonus, healthcare, and a range of employee benefits.
Responsibilities
Meticulous experimental planning and execution to meet program goals.
Timely record keeping of results into data sheets and laboratory note-books.
Regular mining of literature and keeping oneself up to date with developments in field of antibody development.
Compilation and presentation of data in written and oral formats. Active participation in team meetings.
Postdoctoral Research Fellow - Center for Discovery & InnovationHackensack Meridian Health · Nutley, US
Scientist I, Protein BiologyThermo Fisher Scientific · Bangalore, India