The Biochemist III will support the early molecule discovery team by designing and implementing biochemical and biophysical assays to support hit identification, hit triage, and mechanism of action characterization across diverse molecular targets.
Compensation
Compensation Range: $31.00-$34.00 per hour (e.g., the job posting is not necessarily reflective of actual compensation that may be earned, and actual compensation is subject to variation due to such factors as location, education, experience, and skillset).
Responsibilities
Design, develop, and validate biochemical and biophysical assays for hit identification, hit triage, and mechanism of action characterization.
Perform biochemical assays using TR-FRET, fluorescence polarization (FP), AlphaLISA/AlphaScreen, luminescence, and ELISA formats.
Prepare assay reagents, protein dilutions, substrate stocks, and compound serial dilutions.
Execute enzyme activity assays, protein–protein interaction assays, and binding assays with guidance.
Run assays in 384- and 1536-well microplate formats.
Requirements
Master’s Degree in Chemistry, Biochemistry or closely related field
Contribute to new product development by performing bioassays to evaluate recombinant proteins and neutralizing antibodies, including cell-based and binding assays, and support the development, optimization, and validation of new bioassays.
Compensation
The base salary range for this full-time position is $23.00 - 30.75/hr.
Responsibilities
Perform bioassays following established protocols
Develop new bioassays
Contribute to optimization and validation of new bioassays
Perform plate-based testing of proteins in cell-free and cell-based assays
Maintain cancer cell lines using sterile cell culture techniques
Requirements
Bachelor’s degree in science (Biology, Immunology, or other Life Science discipline)
Nice to have: Master’s degree in Life Science
Nice to have: experience in primary cell cultures
Nice to have: two years of experience in performing bioassay
