Bristol Myers Squibb is seeking a technology leader with deep roots in clinical pharmacology and pharmacometrics (CPP) to serve as the Senior Director, Clinical Pharmacology & Pharmacometrics Technology within Research Business Insights & Technology (BI&T). This leader owns the technology products, modeling and scientific-computing platforms, data integrations, workflow automation, and validated operational services that enable CPP work end to end—from quantitative preclinical-to-clinical bridging through clinical PK/PD, dose and regimen decisions, and submission-ready outputs.
Locations (4)
Cambridge Crossing, Massachusetts, United States
Brisbane, California, United States
Princeton, New Jersey, United States
San Diego, California, United States
Compensation
Brisbane - CA - US: $252,640 - $306,137
Cambridge Crossing: $252,640 - $306,137
Princeton - NJ - US: $229,670 - $278,306
San Diego - CA - US: $252,640 - $306,137
Responsibilities
Serve as the single BI&T point of accountability for CPP technology, applications, workflows, and support services end to end
Define and own the multi-year CPP technology strategy, architecture, and product roadmap, aligned with BI&T enterprise standards and R&D scientific priorities
Partner across Research and Development to integrate CPP workflows with the scientific, data, and operational capabilities required for model-informed drug development
Own the lifecycle of CPP applications, modeling environments, scientific-computing infrastructure, reporting pipelines, and operational support, including build/buy/partner decisions
Ensure operational excellence, reliability, governance, and continuous improvement across modeling environments, clinical PK/PD systems, reporting workflows, and submission-support applications
Requirements
Advanced degree (Ph.D. preferred) in Pharmacometrics, Clinical Pharmacology, Pharmaceutical Sciences, Biostatistics, or related quantitative field
Technology leader with deep roots in clinical pharmacology and pharmacometrics (CPP) to serve as the Senior Director, Clinical Pharmacology & Pharmacometrics Technology within Research Business Insights & Technology (BI&T). This leader owns the technology products, modeling and scientific-computing platforms, data integrations, workflow automation, and validated operational services that enable CPP work end to end.
Locations (4)
Cambridge Crossing, Massachusetts, United States
Brisbane, California, United States
Princeton, New Jersey, United States
San Diego, California, United States
Compensation
Brisbane - CA - US: $252,640 - $306,137
Cambridge Crossing: $252,640 - $306,137
Princeton - NJ - US: $229,670 - $278,306
San Diego - CA - US: $252,640 - $306,137
Conceives, executes and effectively manages and communicates multi-disciplinary Clinical Pharmacology development plans and strategies that achieve commercial goals and regulatory requirements for multiple functions.
Responsibilities
Accountable for Phase 1-4 studies design, and clinical pharmacology strategy; acts as the representative for project(s).
Execute strategy, lead teams and various data analyses and interpretation by providing necessary context (including explaining MoA and disease specifics, available relevant internal and external data, analysis plans, interpretation and discussion of model results in the context of research question).
Author regulatory documents including protocols, study reports, population PK reports, exposure-response analyses reports, CTDs, label sections, relevant section of investigator brochures, white papers, and other similar documents.
Leads clinical pharmacology and biopharmaceutics meetings, serve as CLINICAL PHARMACOLOGY representative at Clinical Strategy Team/Asset Development Team and present at various departmental and cross functional teams such as study teams, CLINICAL PHARMACOLOGY leadership team, Journal club.
Drives small teams with members from CLINICAL PHARMACOLOGY functional groups to provide a unified clinical pharmacology position to clinical, CMC and regulatory teams.
Requirements
PhD
Pharm D
Master’s Degree
Bachelor’s Degree
Director, Clinical Pharmacology
Johnson & Johnson Innovative Medicine · Posted Nov 4, 2026
The Clinical Pharmacology (CP) Director role within Clinical Pharmacology & Pharmacometrics (CPP) is to apply and promote clinical pharmacology expertise including the design of clinical pharmacology studies and/or clinical pharmacology components of clinical studies, pharmacokinetics (PK), pharmacodynamics (PD) analysis and reporting, and application of principles of model-informed drug development (MIDD) to studies and programs in all stages of development, ranging from pre-New Molecular Entity (NME) declaration through post-marketing support.
Locations (4)
La Jolla, California, United States
Raritan, New Jersey, United States
Spring House, Pennsylvania, United States
Titusville, New Jersey, United States
Compensation
The anticipated base pay range for this position is : $168,000.00 - $290,950.00
Responsibilities
Serve as the single BI&T point of accountability for CPP technology, applications, workflows, and support services end to end
Define and own the multi-year CPP technology strategy, architecture, and product roadmap
Partner across Research and Development to integrate CPP workflows with scientific, data, and operational capabilities
Own the lifecycle of CPP applications, modeling environments, scientific-computing infrastructure, reporting pipelines, and operational support
Ensure operational excellence, reliability, governance, and continuous improvement across modeling environments, clinical PK/PD systems, reporting workflows, and submission-support applications
Requirements
Advanced degree (Ph.D. preferred) in Pharmacometrics, Clinical Pharmacology, Pharmaceutical Sciences, Biostatistics, or related quantitative field
Planning, completing and/or overseeing the clinical pharmacology and model informed drug development strategy via application of quantitative methods to integrate knowledge of nonclinical data (e.g., metabolism, BCS classification, pharmacology, safety), PK, PD (e.g., biomarker, efficacy, and/or safety), patient characteristics, disease states, competitive landscape, and drug interactions to influence go/no go decisions, support patient sub-population, dose and dosage regimen selection, and optimize study designs throughout drug development.
Translating quantitative knowledge into strategic opportunities with key partners to drive development along the model-informed drug development principles and advocate for innovative strategies.
Planning, completing, interpreting and/or overseeing appropriate analyses (e.g., non-compartmental, population and/or modelling and simulation analysis of PK and/or PD data) of preclinical-clinical translation, dose/exposure-response relationships, to guide dose regimen and optimize study design and overall drug development strategy.
Regulatory input for clinical pharmacology informing strategy, regulatory interactions, labeling and clinical use.
Planning and delivery of scientifically robust and efficient clinical pharmacology strategies for development candidates.
Requirements
PhD in Pharmaceutical Sciences, Clinical Pharmacology, Biomedical Engineering, or relevant Biological Sciences
Nice to have: Multiple publications and presentations