Lead clinical pharmacology strategy and operations for drug development programs, overseeing PK/PD studies, modeling, regulatory interactions, and team management.
Locations (4)
Raritan, New Jersey, United States
Titusville, New Jersey, United States
Spring House, Pennsylvania, United States
La Jolla, California, United States
Compensation
The anticipated base pay range for this position is : $168,000.00 - $290,950.00
Responsibilities
Plan and oversee clinical pharmacology studies and modeling
Analyze PK/PD data and support dose selection
Develop regulatory strategy and documentation
Manage and mentor CPP team members
Collaborate with cross-functional partners
Requirements
PhD in Pharmaceutical Sciences, Clinical Pharmacology, Biomedical Engineering, or relevant Biological Sciences
Lead the Clinical Pharmacology strategy and team within the Clinical Pharmacology & Pharmacometrics division, overseeing study design, data analysis, regulatory strategy, and cross‑functional collaboration to advance drug development programs.
Locations (4)
Raritan, New Jersey, United States
Titusville, New Jersey, United States
Spring House, Pennsylvania, United States
La Jolla, California, United States
Compensation
The anticipated base pay range for this position is : $168,000.00 - $290,950.00
Responsibilities
Plan and oversee clinical pharmacology studies and model‑informed drug development strategy
In addition to base salary, we offer equity, an annual bonus dependent on individual and company performance, and a 6% 401K contribution. You will have a USD $1,500 annual Active Lifestyle Allowance, annual vacation, professional development opportunities, and comprehensive health benefits.
Responsibilities
Leading the clinical pharmacology strategy for assigned therapeutic programs, from first-in-human through Phase 2 and into late-stage planning
Applying model-informed drug development (MIDD) approaches to justify doses and dosing intervals, optimize study designs, and support go/no-go decisions
Recommending first-in-human starting doses and escalation schemes by integrating nonclinical PK/PD, toxicology, target engagement and translational biomarker data
Building integrated clinical pharmacology plans that address PK, PD, exposure-response, dose and regimen selection, immunogenicity, intrinsic and extrinsic factors, and formulation or route changes
Executing pharmacometric methodologies such as population PK/PD, PBPK, and QSP to understand exposure-response relationships and define quantitative criteria to support data-driven decisions
Lead the clinical pharmacology strategy for therapeutic programs, applying model-informed drug development approaches to optimize trial designs, justify dose selections, and support regulatory interactions.
Compensation
AbCellera’s hiring range for this role is CAD $170,000 - $200,000 annually, commensurate with your education and job-related knowledge, skills, and experience. In addition to base salary, we offer equity, an annual bonus dependent on individual and company performance, and a 6% (non-match) RRSP contribution.
Responsibilities
Lead the clinical pharmacology strategy for assigned therapeutic programs
Apply model-informed drug development approaches to justify doses and dosing intervals
Recommend first-in-human starting doses and escalation schemes
Build integrated clinical pharmacology plans
Execute pharmacometric methodologies such as population PK/PD, PBPK, and QSP
Expert in mathematical modelling and PK/PD to help shape project strategies and drive critical decisions across the drug discovery portfolio using quantitative approaches for cardiovascular, renal and metabolic diseases.
Responsibilities
Shape project strategies and drive critical decisions across the drug discovery portfolio
Contribute to drug project teams, providing quantitative insights for target and molecule selection, dosing strategies, and translational development decisions
Design and oversee the execution of complex studies in preclinical disease models
Synthesize data from multiple sources to predict human pharmacokinetics and pharmacodynamics
Influence the definition of efficacious exposure and dosing regimens
Requirements
PhD in pharmacokinetics, pharmacology, mathematics, or related field
Nice to have: preclinical or translational setting
Principal Scientist, Clinical PharmacologyAbCellera · US