Support development of recombinant therapeutic antibody drug candidates through development, optimization, qualification, and transfer of analytical methods used for characterization of investigational products.
Compensation
The estimated pay scale for Scientist I ( Analytical Development) role based in California, is $100,412 - $120,515 per year. Additionally, the position is eligible to participate in up to 8% of the company bonus pool.
Responsibilities
Plan and perform various analytical techniques, including SE-HPLC, SEC-MALS, CEX-HPLC, cIEF, SDS-PAGE, CE-SDS, ELISA, MSD, in vitro cell-based assays, and qPCR
Analyze, interpret, and present analytical data to drive technical understanding, meet project objectives, troubleshoot, and make recommendations
Discuss experimental plans and results with project team members
Develop, write, and review technical documents such as analytical test methods, method qualification protocols, and method qualification reports
Collaborate and coordinate activities across functional groups involved in antibody therapeutics development, including discovery, process development, and project management teams
Support the development and execution of biomarker strategies across early-stage clinical programs at ModeX Therapeutics.
Responsibilities
Support the development and execution of clinical biomarker plans for ModeX’s clinical studies.
Contribute to the selection, validation, and implementation of biomarker assays, including flow cytometry, immunophenotyping, cytokine analyses, soluble biomarkers, genomics, transcriptomics, and tissue-based assays.
Monitor biomarker sample quality, assay performance, and data delivery timelines.
Manage activities and deliverables of external laboratories, CROs, and academic collaborators.
Perform biomarker data review, analysis, interpretation, and visualization to support study objectives and decision-making.
A hands-on role combining advanced data analytics with laboratory-based assay development in a cross-functional setting to support characterization of cell-based products.
Compensation
Pay Range: $102,800 - $154,200. This role is eligible for an annual bonus and annual equity awards.
Responsibilities
Independently conceptualize, develop, and deploy analytical solutions that support characterization of cell-based products
Perform laboratory experiments supporting analytical method development for gene and cell therapy products, and apply statistical analyses to assess specificity, sensitivity, linear range, precision, and accuracy
Analyze complex experimental and process data, and create clear visualizations and present findings and recommendations to technical teams and management
Execute test methods supporting Process Development activities to support process improvements
Author and review SOPs, protocols, technical reports, and transfer and qualification documentation, and contribute analytical content to regulatory filings
Conducting molecular biology and protein engineering on a diverse array of biological drug candidates to support discovery and development campaigns for serious and rare disease patients.
Compensation
$80,000.00-102,000.00 Annual
Responsibilities
Design, execute and optimize molecular biology experiments to support lead candidate selection
Validate and perform DNA based assays (DNA purification, PCR, and Quality and Quantification of DNA)
Culture mammalian cell lines and conduct transient transfections of mammalian cells for protein expression
Culture bacterial cell lines and conduct protein expression and purification
Interact and collaborate with multidisciplinary team to advance the project
Requirements
Master’s degree in Molecular Biology or related field
Bachelor’s degree in Molecular Biology or related field
Scientist supporting clinical testing across multiple vaccine programs and all phases of clinical development, providing scientific and technical expertise for high-quality and timely laboratory testing.
Compensation
The annual base salary for this position ranges from $79,400.00 to $132,400.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 7.5% of the base salary.
Responsibilities
Plan, manage, and coordinate laboratory and operational activities in support of clinical studies
Serve as a subject matter expert for molecular diagnostic assays and provide technical guidance for assay execution, troubleshooting, and laboratory operations
Oversee clinical data review and monitor assay quality, laboratory compliance, and assay performance
Support assay operations, including reagent maintenance, qualification activities, proficiency monitoring, and testing execution
Design and execute non-clinical experiments in support of clinical assays, including assay development, validation/qualification, and reagent or method evaluations
Lead clinical and preclinical immunology studies supporting the advancement of Vaxart’s mucosal vaccine platform.
Compensation
In accordance with California’s Pay Transparency law, Vaxart’s base salary range for this position is approximately $130,000 - $150,000 USD annually.
Responsibilities
Independently design, optimize, execute and analyze cellular and humoral immunology assays including multiparameter flow cytometry (10+ colors), MesoScale Discovery (MSD), and neutralization assays using human biospecimens.
Design and optimize ex vivo immune profiling studies using human PBMCs and other clinical samples.
Lead and manage external and internal in-vitro and in-vivo pre-clinical studies.
Develop and optimize laboratory methods and SOPs.
Maintain detailed experimental records and ensure data integrity and reproducibility.
Requirements
PhD in Immunology, Cell Biology, or relevant discipline
Nice to have: Experience working with clinical samples in a regulated or industry environment
Scientist I (Analytical Development)NewGrifols · San Carlos, US
Associate Scientist, AutomationNewStylus Medicine · Cambridge, US
Scientist II, Translational ScienceNewModeX Therapeutics · Weston, US
Research Scientist, ScreeningNewPromega · Madison, US
Scientist II, ImmunologyVaxart · South San Francisco, US